Greggs Appliances Case Study - 1119 Words

Case Study 1-6 Introduction This issue for case study 1-6 is brought to us by Steve Nelson and the company of the Gregg’s Appliances, Inc. The HH Gregg Company was founded on April 15, 1955 in Indianapolis by Henry Harold Gregg and his wife. The initial store was an 800 square feet appliance showroom and office. Since then the company has expanded and with that expansion the company needed more and more information technology in order to harness the power of the information they had acquired. But in 2006 the current CIO, Steve Nelson, was facing a deadline. The deadline was the HP, which was Gregg’s principal information technology vendor, has chosen to discontinue support for its line of HP 300 mainframe processors. Gregg’s relied†¦show more content†¦The bonuses to this choice would be lower costs compared to Delphi and Sentra, Gregg’s could maintain current business processes and there is limited training required. But the Texas Firm UNIX platform does not mo ve Gregg’s to an industry standard and it requires significant development staff time. The other UNIX choice was from Ex-ADI costing $4-$5 million. The process for this change would be to hire programmers and re-write into a UNIX platform internally. The biggest benefit to this selection was that it allows for phase-in implementation, which means no business will be stopped. It is also much cheaper than Delphi and Sentra options. The software will also be high adaptable and customizable and limited training will be required. But this will not move the company to an â€Å"industry standard† and nothing will seem new. There are several big risks when changing important software in a large company. It could lead to a sudden halt of the business during the deployment because of a failed database, a bad internet connection or the inability of staff to input or process orders. The system might not be able to handle the work load. Lastly, there could be an unexpected complete system shutdown. There are also other costs to consider. Along with the implementation and annual maintenance costs outlined in the summary, Nelson Must also consider other costs including: * Training costs * Testing costs * Costs of lostShow MoreRelatedManaging Information Technology (7th Edition)239873 Words   |  960 PagesCONTENTS: CASE STUDIES CASE STUDY 1 Midsouth Chamber of Commerce (A): The Role of the Operating Manager in Information Systems CASE STUDY I-1 IMT Custom Machine Company, Inc.: Selection of an Information Technology Platform CASE STUDY I-2 VoIP2.biz, Inc.: Deciding on the Next Steps for a VoIP Supplier CASE STUDY I-3 The VoIP Adoption at Butler University CASE STUDY I-4 Supporting Mobile Health Clinics: The Children’s Health Fund of New York City CASE STUDY I-5 Data

Developing Flexible Software Using Agent Oriented Software...

Developing Flexible software using Agent Oriented Software Engineering BY: Hussain ul Abideen 01617974 Question#1: Which topics discussed in the lecture does this paper relate to? What problem(s) are the authors attempting to solve? This theme is about Creating Adaptable programming utilizing Operator situated Programming Building, and the issue is Cutting edge programming frameworks search developing adaptability necessities for adjusting, scaling, and incorporating with different frameworks. Al however, it s regularly questionable how to accomplish the objective that crucial adaptability amid programming framework advancement, complex cooperation’s and practices. Specialist situated programming building is the strategy which†¦show more content†¦Through conceptual associations and communication conventions, operators bolster the combination of new and even already obscure framework elements amid runtime. These are the main topic on which Author focus. †¢ Basic Agent Oriented Concepts †¢ Comparison to other software engineering paradigms †¢ Agent Platform Question#2: Give a brief summary of the results presented in this paper. Basic Agent Oriented Concepts: The initial phase in comprehension AOSE is to correctly recognize and characterize the key ideas and ideas of operator based processing. This methodology depends on the idea of the product operator, which represents the focal method for reflection in AOSE. A product specialist is characterized as an embodied delicate product substance with one or more indicated objectives. To satisfy these objectives, an operator demonstrates self-ruling conduct and interfaces persistently with its surroundings and different specialists. Increasing encapsulation in software development paradigms Monolithic program Structured development object-oriented development agent-oriented development A software entity’s behavior is: Accessible Encapsulated Encapsulated Encapsulated A software entity’s state is: Accessible Accessible Encapsulated Encapsulated When does a software entity execute? Always accessible Always accessible (via calls) Always accessible (via messages) Encapsulated—agent decides on the basis of its goals Why does a software entity execute? Always accessible

Characterising Mesenchymal Stem Cells Health And Social Care Essay Free Essays

This abstract is related to a seminar delivered by Dr. Platt sing Isolation of Mesenchymal root cells from kids ‘s dentitions and geographic expedition of their function in tissue fix. The seminar provided a comprehensive overview of root cells before concentrating on Mesenchymal root cells ( MSCs ) from the dental mush of kids deciduous dentitions. We will write a custom essay sample on Characterising Mesenchymal Stem Cells Health And Social Care Essay or any similar topic only for you Order Now By definition, â€Å" a root cell is an unspecialised cell that can both self-renew and distinguish into functional phenotypes † ( Grad et al. , 2012 ) . Stem cells are divided into two chief groups: embryologic root cells ( ESCs ) and big root cells ( ASCs ) ( of bodily beginning ) . ESCs derive from blastocyte phase and are capable to give rise to all sorts of cells. Therefore, ESCs are considered pluripotent. On the contrary, ASCs are merely multipotent because they have restricted distinction potency ( Barbara et al. , 2011 ) . Stem cells give rise to different cell types, and are classii ¬?ed into totipotent, pluripotent, and multipotent harmonizing to their grade of distinction or potency ( Arce et al. , 2007 ) . Totipotency is the ability to organize all cell types including the full foetus and placenta. Pluripotency is the ability to organize several cell types of all three sources beds ( exoderm, mesoblast and entoderm ) excepting excess embryologic tissues. Multip otency is the ability of giving rise to a limited scope of cells and tissues appropriate to their location such as Mesenchymal root cells ( MSCs ) ( Mirzapour et al. , 2011 ) . MSCs are ASCs with mesoblastic and neuroectodermal beginning ( Barbara et al. , 2011 ) .For case, MSCs possess an drawn-out grade of malleability compared to other ASCs populations, including the ability to distinguish in vitro into non-mesodermal cell types such as nerve cells and astrocytes. MSCs, in add-on to their multipotency, are easy to be isolated and cultured in vitro and they do non seemingly represent an ethical issue based on their beginning of beginning ( Barbara et al. , 2011 ) . The first unequivocal markers of MSCs were proposed in a new survey of Pittenger et al. , the group who besides developed consistent in vitro checks of MSC multipotentiality towards bone, gristle, and fat line of descents ( Pittenger et al. , 1999 ) . These MSC markers correspond to CD105 and CD73 molecules, severally. Of note, CD stands for â€Å" bunch of distinction † , the standard terminology for cell surface molecules ( Boxall et al. , 2012 ) . These two markers alongside CD90 are positively expressed on MSCs and remain the primary molecules used to place MSCs by the International Society of Cell Therapy ( ISCT ) place statement ( Dominici et al. , 2006 ) . The ISCT place statement besides advices that MSCs should be negative for the look of CD11b or CD14, CD19 or CD79a, CD34, CD45, and HLA-DR ( Dominici et al. , 2006 ) . MSCs harvested from assorted beginnings, such as bone marrow, adipose tissue and dental mush, have been tested for their periodontic tissue regeneration potency. MSCs have shown improved efficaciousness and duplicability compared to current clinical pattern ( Tobita A ; Mizuno, 2011 ) . Tooth derived cells are readily accessible and supply an easy and minimally invasive manner to obtain and hive away root cells for future usage. Obtaining root cells from human exfoliated deciduous dentitions ( SHED ) of kids is simple and convenient. Every kid loses primary dentitions, which creates the perfect chance to retrieve and hive away this convenient beginning of root cells — should they be needed to handle future hurts or complaints and nowadayss a far better alternate to merely flinging the dentition or hive awaying them as souvenir from the yesteryear. Stem cells can besides be recovered from developing wisdom dentitions and lasting dentition. Persons have different chances at different phases of their life to bank these valuable cells ( Arora et al. , 2009 ) . However, it is best to retrieve root cells when a kid is immature and healthy and the cells are strong and proliferative ( Arora et al. , 2009 ) .In fact, the research of Dr. Platt showed that dental mush cells from 2 twelvemonth old female have increased attachment to plastic than those of 3 twelvemonth old female after 11-days post-seeding. SHED are instead freshly discovered MSC ( Miura et al. , 2003 ) . When compared with grownup bone marrow stromal root cells ( BMSSCs ) and dental mush root cells ( DPSCs ) , SHED of kids showed a higher proliferation rate ( Fig.A 1 ) and a higher figure of population duplicating ( Miura et al. , 2003 ) and interestingly express many of nervous cell markers in the cell civilization ( Huang et al. 2009 ) . Therefore, root cells from dental mush ( largely SHED from younger kids ) demonstrate increased multipotentiality and capableness to renew multiple dental/periodontal tissues in vitro and in vivo compared with MSCs from other niches ( Huang, 2009 ) . Fig1: Datas obtained from Miura et al. , 2003 Dental mush root cells can be preserved for long periods without losing their multipotential distinction ability ( Laino et al. , 2005 ) . The dental mush plays a major function in tooth regeneration after hurt, by take parting in a procedure called reparative dentinogenesis. An ideal signifier of therapy might dwell of regenerative attacks in which diseased or necrotic mush tissues are removed and replaced with regenerated mush tissues to regenerate the dentition ( Sun et al. , 2010 ) . In fact, Dr. Platt isolated MSCs from deciduous dental mush ( SHELD ) by the enzyme-digestion method. This method involves the aggregation of the mush tissue under unfertile conditions, the digestion with appropriate enzymes ( collagenase, dispase, and trypsin ) for 90min at 37EsC/5 % CO2, the seeding in civilization dishes incorporating a particular medium supplemented with necessary additives, and so the incubation at 37A °C. It can be concluded from Dr. Platt research informations that Mesenchymal root cells from kids dental mush are fictile adherent cells with a fibroblastic morphology. These cells signifier settlements in vitro which is declarative of a stem/progenitor cell. In fact, it was proved that these mush cells have multi-lineage distinction potency in vitro, into several cell types including nervous primogenitors, chondrocytes, endothelocytes, adipocytes, smooth musculus cells and bone-forming cells ( Sloan A ; Waddington, 2009 ) . To day of the month, several surgical techniques have been developed to renew periodontic tissues. The clinical result of presently available techniques is undependable, although assorted intervention modes have shown regenerative potency. Progresss in root cell biological science have yielded promising consequences in vitro and in vivo, proposing that future applications in dental medicine may be accomplishable ( Tobita A ; Mizuno, 2011 ) . How to cite Characterising Mesenchymal Stem Cells Health And Social Care Essay, Essay examples